Pyridoxine Dicaprylate

INCI: PYRIDOXINE DICAPRYLATE [^1_11]

CAS Number
106483-04-9 [^1_11][^1_12]
Function
Skin conditioning — oil-soluble Vitamin B6 derivative with improved percutaneous absorption; effective for acne, rough skin, dandruff, sunburn [^1_12]
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted under general cosmetic provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
high
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Enhanced skin penetration by design; ensure use levels are appropriate given higher bioavailability [^1_12]

⚠️
Concern Level: Low

Frequently Asked Questions

Is Pyridoxine Dicaprylate safe in cosmetics?

Enhanced skin penetration by design; ensure use levels are appropriate given higher bioavailability [^1_12] The EU classifies Pyridoxine Dicaprylate as "permitted". Safety rating: GOOD.

Is Pyridoxine Dicaprylate allowed in the EU?

Pyridoxine Dicaprylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Pyridoxine Dicaprylate do in cosmetics?

Pyridoxine Dicaprylate functions as: Skin conditioning — oil-soluble Vitamin B6 derivative with improved percutaneous absorption; effective for acne, rough skin, dandruff, sunburn [^1_12]. It is classified as a cosmetic ingredient in our database. CAS number: 106483-04-9 [^1_11][^1_12].

What is the Margin of Safety for Pyridoxine Dicaprylate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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