Is Quaternium-71 safe in cosmetics?
Quaternium-71 has a safety rating of "MODERATE" in our database. EU status: permitted. US status: permitted.
Moderate
Cosmetic Ingredient
Quaternium-71
Also known as: alpha-(2-Chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol, 5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-, 5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-chlorophenyl)-, BRN 5972869, Caswell No. 207AA (+7 more)
INCI: QUATERNIUM-71
Quaternium-71 (CAS 60168-88-9) is a cosmetic cosmetic ingredient functioning as Antistatic agent, hair conditioning agent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 60168-88-9 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Quaternium-71 is classified GHS CMR hazard (H302, H320, H361, H371, H373, H361fd, H362, H411) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu_status; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
Antistatic agent, hair conditioning agent
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
(2-chlorophenyl)-(4-chlorophenyl)-pyrimidin-5-ylmethanol
InChIKey
NHOWDZOIZKMVAI-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Quaternium-71.
Calculate MoS for your specific formulation with the MoS Calculator.
EU CLP Annex VI Harmonized Classification
Legally binding harmonized classification per Regulation (EC) No 1272/2008 (CLP) Annex VI.
Signal Word
Warning
Pictograms
Health HazardEnvironmental Hazard
Hazard Class and Category
Repr. 2; Lact.; Aquatic Chronic 2
Hazard Statements
- H361fd
- H362 May cause harm to breast-fed children
- H411 Toxic to aquatic life with long lasting effects
Inserted via ATP: CLP00
EU CosIng Annex Listing
European Commission CosIng database Annex references per Regulation (EC) No 1223/2009.
Annex II — Prohibited
Ref: 1075
(EC) 2009/1223
CMR: Reprotoxic Cat. 2()
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (II - Prohibited)
ASEAN Cosmetic Directive (II)
Ref: 1075
BRIN Brazil/India Cosmetics
Brazil: Prohibited
India: Prohibited (GNRAS)
Additional Jurisdictional Restrictions (1)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| KR | prohibited | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (2)
Carcinogen Classification
No indication of carcinogenicity to humans (not listed by IARC).
Source: Toxin and Toxin Target Database (T3DB)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Biocide
Regulatory List Membership (2)
EU Banned in Cosmetics
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Quaternium-71.
Regulatory Flags
eu_banned_cosmetics
eu_cosing_listed
Known Synonyms
alpha-(2-Chlorophenyl)-alpha-(4-chlorophenyl)-5-pyrimidinemethanol
5-Pyrimidinemethanol, alpha-(2-chlorophenyl)-alpha-(4-chlorophenyl)-
5-Pyrimidinemethanol, .alpha.-(2-chlorophenyl)-.alpha.-(4-chlorophenyl)-
BRN 5972869
Caswell No. 207AA
Compound 56722
(+-)-2,4'-Dichloro-alpha-(pyrimidin-5-yl)benzhydryl alcohol
EINECS 262-095-7
EPA Pesticide Chemical Code 206600
Rimidin
UNII-O088GU930Q
EL 222
Chemical Function
Biocide
Regulatory Lists
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; agricultural; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Pesticides
active_ingredient; Europe; Pesticides
active_ingredient; Australia
detected; general_crops; Pesticides; residue
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
FENARIMOL
ChEMBL ID
CHEMBL28971
Frequently Asked Questions
Is Quaternium-71 allowed in the EU?
Quaternium-71 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Quaternium-71 do in cosmetics?
Quaternium-71 functions as: Antistatic agent, hair conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 60168-88-9.
Is Quaternium-71 used outside cosmetics?
Quaternium-71 also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Quaternium-71 have different safety status in cosmetics vs industrial chemicals?
Quaternium-71 is classified GHS CMR hazard (H302, H320, H361, H371, H373, H361fd, H362, H411) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Quaternium-71 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Related Ingredients
2-Hydroxypropylcarbamato Amodimethicone
Excellent
Same category
Hair conditioning; modified aminosili...
Acetamidoamodimethicone
Excellent
Same category
Hair conditioning agent (film-forming...
Glyceryl Dioleate/Linoleate/Linolenate
Excellent
Same category
Hair conditioning agent
Gondoic Acid
Excellent
Same category
Hair conditioning
Hydroxypropyldimethicone
Excellent
Same category
Skin/hair conditioning (silicone poly...
Hydroxypropyltrimonium Inulin
Excellent
Same category
Antistatic, hair conditioning
(20S)-Protopanaxadiol
Moderate
Similar safety
(Cnidium Officinale/Coptis Chinensis/Glycyrrhiza Uralensis) Root Extract
Moderate
Similar safety
Skin conditioning
(Cryptomeria Japonica/Chamaecyparis Obtusa) Stem Ferment Extract
Moderate
Similar safety
Antimicrobial, antioxidant, humectant
(Eclipta Prostrata/Houttuynia Cordata) Leaf Extract
Moderate
Similar safety
Skin conditioning
(Lepidium Meyenii/Sarcodon Aspratus) Root Water
Moderate
Similar safety
Skin conditioning
(Licorice/Reynoutria Japonica) Root/Stem Extract
Moderate
Similar safety
Skin conditioning, antioxidant
QUERCUS ALBA BARK
Good
Browse nearby
Skin Conditioning
QUERCUS INFECTORIA GALL EXTRACT
Good
Browse nearby
Anti-sebum, Astringent, Skin Conditio...
QUILLAJA SAPONARIA BARK EXTRACT
Good
Browse nearby
Anti-seborrheic, Cleansing, Foaming, ...
Is Quaternium-71 in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Quaternium-71 in your formulation.