Quaternium-80

INCI: QUATERNIUM-80

CAS Number
134737-05-6
Function
Antistatic Agent, Hair Conditioning Agent, Skin Conditioning Agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Listed in FDA GSRS. No specific restrictions. LD50 >5,000 mg/kg, Ames negative.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Well-established cationic silicone polymer with long use history showing low toxicity (LD50 >5,000 mg/kg, Ames negative) and no specific regulatory restrictions.

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Concern Level: Low

Frequently Asked Questions

Is Quaternium-80 safe in cosmetics?

Well-established cationic silicone polymer with long use history showing low toxicity (LD50 >5,000 mg/kg, Ames negative) and no specific regulatory restrictions. The EU classifies Quaternium-80 as "permitted". Safety rating: GOOD.

Is Quaternium-80 allowed in the EU?

Quaternium-80 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Quaternium-80 do in cosmetics?

Quaternium-80 functions as: Antistatic Agent, Hair Conditioning Agent, Skin Conditioning Agent. It is classified as a cosmetic ingredient in our database. CAS number: 134737-05-6.

What is the Margin of Safety for Quaternium-80?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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