Retinyl Acetate

INCI: RETINYL ACETATE

CAS Number
127-47-9 [^1_7]
Function
Skin conditioning; antioxidant (Vitamin A ester, converts to retinol in skin) [^1_8]
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
EU Max Conc. 0.05%
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted cosmetic ingredient; no concentration limits; also GRAS for food use

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Classified Repr. 1B, H360 (may damage fertility or unborn child) due to teratogenic risk from excess Vitamin A [^1_10]; photosensitivity; requires controlled storage (light/air sensitive) [^1_8]; SCCS concern about exceeding EFSA upper intake levels when combined with dietary exposure [^1_11]

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Concern Level: Low

Frequently Asked Questions

Is Retinyl Acetate safe in cosmetics?

Classified Repr. 1B, H360 (may damage fertility or unborn child) due to teratogenic risk from excess Vitamin A [^1_10]; photosensitivity; requires controlled storage (light/air sensitive) [^1_8]; SCCS concern about exceeding EFSA upper intake levels when combined with dietary exposure [^1_11] The EU classifies Retinyl Acetate as "restricted". Safety rating: GOOD.

Is Retinyl Acetate allowed in the EU?

Retinyl Acetate EU regulatory status: restricted. Maximum allowed concentration: 0.05%. This is based on EU Regulation 1223/2009 and its amendments.

What does Retinyl Acetate do in cosmetics?

Retinyl Acetate functions as: Skin conditioning; antioxidant (Vitamin A ester, converts to retinol in skin) [^1_8]. It is classified as a cosmetic ingredient in our database. CAS number: 127-47-9 [^1_7].

What is the Margin of Safety for Retinyl Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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