Is 5-Methyl-Beta-Ionone safe in cosmetics?
5-Methyl-Beta-Ionone has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
5-Methyl-Beta-Ionone
Also known as: 1-Penten-3-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, beta methyl ionone, Cetone, beta-, EINECS 204-843-7, FEMA No. 2712 (+7 more)
INCI: 5-METHYL-BETA-IONONE
5-Methyl-Beta-Ionone (CAS 127-43-5) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
Function
Fragrance (perfuming)
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
(E)-1-(2,6,6-trimethylcyclohexen-1-yl)pent-1-en-3-one
InChIKey
LMWNGLDCJDIIBR-CMDGGOBGSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted by FDA; IFRA-regulated
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for 5-Methyl-Beta-Ionone.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (3)
JECFA Number
399
Source: WHO/JECFA
JECFA Evaluation
beta-CETONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/335 (1998)
Source: WHO/JECFA
JECFA Evaluation
METHYL-beta-IONONE | 2002 | No safety concern at current levels of intake when used as a flavouring agent | Secondary components do not raise a safety concern | TRS 913-JECFA 59/111 | FAS 42-JECFA 51/335 (1998)
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Flavouring and nutrient
Fragrance
Regulatory List Membership (2)
IFRA Fragrance Transparency List
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for 5-Methyl-Beta-Ionone — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
potential-allergen
fragrance-component
ifra_fragrance
fda_food_additive
Known Synonyms
1-Penten-3-one, 1-(2,6,6-trimethyl-1-cyclohexen-1-yl)-
beta methyl ionone
Cetone, beta-
EINECS 204-843-7
FEMA No. 2712
beta-Ionone, methyl-
beta-Iraldeine
beta-Methylionone
NSC 163995
1-(2,6,6-Trimethyl-1-cyclohexen-1-yl)-1-penten-3-one
5-(2,6,6-Trimethyl-1-cyclohexenyl)-4-penten-3-one
UNII-54PXU8D4R5
Chemical Function
Fragrance
Flavouring and nutrient
Regulatory Lists
Europe
IFRA Transparency
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is 5-Methyl-Beta-Ionone allowed in the EU?
5-Methyl-Beta-Ionone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does 5-Methyl-Beta-Ionone do in cosmetics?
5-Methyl-Beta-Ionone functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 127-43-5.
Is 5-Methyl-Beta-Ionone used outside cosmetics?
5-Methyl-Beta-Ionone also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check 5-Methyl-Beta-Ionone compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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Chemical family
Fragrance (Perfuming)
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Chemical family
Fragrance ingredient
Alpha-Methyl-Alpha-Ionone
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Chemical family
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