Is Rhodinyl Isobutyrate safe in cosmetics?
Rhodinyl Isobutyrate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Rhodinyl Isobutyrate
Also known as: (+/-)-Rhodinyl Isobutyrate
INCI: RHODINYL ISOBUTYRATE
Rhodinyl Isobutyrate (CAS 138-23-8) is a cosmetic cosmetic ingredient functioning as Fragrance (perfuming) — floral/fruity type. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 138-23-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance (perfuming) — floral/fruity type
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(3S)-3,7-dimethyloct-7-enyl] 2-methylpropanoate
InChIKey
KHCGLDOOFYZQKU-ZDUSSCGKSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
GRAS for flavoring (FEMA 2983); permitted in cosmetics
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Rhodinyl Isobutyrate.
Calculate MoS for your specific formulation with the MoS Calculator.
HRIPT Human Patch Test Studies
1 human repeat insult patch test aggregated from dermatological literature.
| Test Type | N | Sensitized | Dose µg/cm² | NESIL µg/cm² | Potency |
|---|---|---|---|---|---|
| HMT | - | 0 | 2700 | - | - |
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
74
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
JECFA Evaluation
RHODINYL ISOBUTYRATE | 1997 | No safety concern at current levels of intake when used as a flavouring agent | TRS 884-JECFA 49/64 | FAS 40-JECFA 49/329
Source: Joint FAO/WHO Expert Committee on Food Additives (JECFA)
Expert Verdict
Expert safety assessment and concern-level summary for Rhodinyl Isobutyrate.
Regulatory Flags
potential-allergen
fragrance-component
fda_food_additive
jecfa_safe
Known Synonyms
(+/-)-Rhodinyl Isobutyrate
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Rhodinyl Isobutyrate allowed in the EU?
Rhodinyl Isobutyrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Rhodinyl Isobutyrate do in cosmetics?
Rhodinyl Isobutyrate functions as: Fragrance (perfuming) — floral/fruity type. It is classified as a cosmetic ingredient in our database. CAS number: 138-23-8.
Compliance Tools
Check Rhodinyl Isobutyrate compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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