Rice SH-Polypeptide-3

INCI: RICE SH-POLYPEPTIDE-3

CAS Number
148348-15-6 [^1_12]
Function
Skin Conditioning, Hair Conditioning — KGF (Keratinocyte Growth Factor) analog [^1_13]
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status restricted
US Notes Not specifically restricted; permitted under general cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Former name: rh-Oligopeptide-5; stimulates epithelial cell proliferation; involved in early hair growth [^1_13]; recommended to perform patch test before use [^1_14]

⚠️
Concern Level: Low

Frequently Asked Questions

Is Rice SH-Polypeptide-3 safe in cosmetics?

Former name: rh-Oligopeptide-5; stimulates epithelial cell proliferation; involved in early hair growth [^1_13]; recommended to perform patch test before use [^1_14] The EU classifies Rice SH-Polypeptide-3 as "permitted". Safety rating: GOOD.

Is Rice SH-Polypeptide-3 allowed in the EU?

Rice SH-Polypeptide-3 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Rice SH-Polypeptide-3 do in cosmetics?

Rice SH-Polypeptide-3 functions as: Skin Conditioning, Hair Conditioning — KGF (Keratinocyte Growth Factor) analog [^1_13]. It is classified as a cosmetic ingredient in our database. CAS number: 148348-15-6 [^1_12].

What is the Margin of Safety for Rice SH-Polypeptide-3?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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