Salvia Officinalis (Sage) Leaf

INCI: SALVIA OFFICINALIS (SAGE) LEAF

CAS Number
84082-79-1 (generic)
Function
No cosmetic function officially reported by wINCI Dictionary; used as a botanical raw material
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes GRAS as natural seasoning/flavoring (21 CFR ยง182.10); no specific cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Thujone content (neurotoxic at high doses); terpene-driven sensitization risk; estrogenic activity demonstrated in animal studies at oral doses โ‰ฅ100 mg/kg; contraindicated in pregnancy (oral)

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Salvia Officinalis (Sage) Leaf safe in cosmetics?

Thujone content (neurotoxic at high doses); terpene-driven sensitization risk; estrogenic activity demonstrated in animal studies at oral doses โ‰ฅ100 mg/kg; contraindicated in pregnancy (oral) The EU classifies Salvia Officinalis (Sage) Leaf as "permitted". Safety rating: GOOD.

Is Salvia Officinalis (Sage) Leaf allowed in the EU?

Salvia Officinalis (Sage) Leaf EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Salvia Officinalis (Sage) Leaf do in cosmetics?

Salvia Officinalis (Sage) Leaf functions as: No cosmetic function officially reported by wINCI Dictionary; used as a botanical raw material. It is classified as a cosmetic ingredient in our database. CAS number: 84082-79-1 (generic).

What is the Margin of Safety for Salvia Officinalis (Sage) Leaf?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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