Sec-Butyl Acetate

INCI: SEC-BUTYL ACETATE

CAS Number
105-46-4 [^1_11][^1_12]
Function
Solvent (nail lacquers, coatings) [^1_11]
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Listed on TSCA; used in nail enamels; OSHA PEL: TWA 200 ppm [^1_12]

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

⚠ Highly flammable (flash point 16°C); CNS depressant at high inhalation exposure; respiratory and mucous membrane irritant; requires adequate ventilation during use; NFPA Health rating: 1, Flammability: 3 [^1_11][^1_13]

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Sec-Butyl Acetate safe in cosmetics?

⚠ Highly flammable (flash point 16°C); CNS depressant at high inhalation exposure; respiratory and mucous membrane irritant; requires adequate ventilation during use; NFPA Health rating: 1, Flammability: 3 [^1_11][^1_13] The EU classifies Sec-Butyl Acetate as "permitted". Safety rating: MODERATE.

Is Sec-Butyl Acetate allowed in the EU?

Sec-Butyl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sec-Butyl Acetate do in cosmetics?

Sec-Butyl Acetate functions as: Solvent (nail lacquers, coatings) [^1_11]. It is classified as a cosmetic ingredient in our database. CAS number: 105-46-4 [^1_11][^1_12].

What is the Margin of Safety for Sec-Butyl Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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