sh-Polypeptide-6

INCI: SH-POLYPEPTIDE-6

CAS Number
Not assigned / not publicly listed
Function
Humectant, Skin Conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; general cosmetic ingredient (not a drug); no CIR monograph published

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Immunosuppressive mechanism โ€” theoretical concern for long-term barrier immune function; no in-vivo toxicity data publicly available

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is sh-Polypeptide-6 safe in cosmetics?

Immunosuppressive mechanism โ€” theoretical concern for long-term barrier immune function; no in-vivo toxicity data publicly available The EU classifies sh-Polypeptide-6 as "restricted". Safety rating: GOOD.

Is sh-Polypeptide-6 allowed in the EU?

sh-Polypeptide-6 EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does sh-Polypeptide-6 do in cosmetics?

sh-Polypeptide-6 functions as: Humectant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly listed.

What is the Margin of Safety for sh-Polypeptide-6?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is sh-Polypeptide-6 in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for sh-Polypeptide-6 in your formulation.