sh-Polypeptide-69

INCI: SH-POLYPEPTIDE-69

CAS Number
Not assigned / not publicly listed
Function
Skin Protecting ; stimulates collagen synthesis, inhibits MMP-mediated ECM degradation, improves DEJ
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific restriction; general cosmetic ingredient; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Marketed by Evonik; at recommended concentrations appears well-tolerated; verify lot-to-lot consistency of recombinant production

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Concern Level: Low

Frequently Asked Questions

Is sh-Polypeptide-69 safe in cosmetics?

Marketed by Evonik; at recommended concentrations appears well-tolerated; verify lot-to-lot consistency of recombinant production The EU classifies sh-Polypeptide-69 as "permitted". Safety rating: GOOD.

Is sh-Polypeptide-69 allowed in the EU?

sh-Polypeptide-69 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does sh-Polypeptide-69 do in cosmetics?

sh-Polypeptide-69 functions as: Skin Protecting ; stimulates collagen synthesis, inhibits MMP-mediated ECM degradation, improves DEJ. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned / not publicly listed.

What is the Margin of Safety for sh-Polypeptide-69?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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