sh-Polypeptide-93

INCI: SH-POLYPEPTIDE-93

CAS Number
Not assigned
Function
Anti-aging, firming, smoothing, regeneration booster — recombinant human CTGF (Connective Tissue Growth Factor) analog, 324 amino acids
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes No specific restriction; general cosmetic use permitted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Growth factor activity (CTGF) — theoretical concern re: unintended fibrotic signaling if penetration occurs; synonym: Clairesome-CT

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Concern Level: Low

Frequently Asked Questions

Is sh-Polypeptide-93 safe in cosmetics?

Growth factor activity (CTGF) — theoretical concern re: unintended fibrotic signaling if penetration occurs; synonym: Clairesome-CT The EU classifies sh-Polypeptide-93 as "permitted". Safety rating: GOOD.

Is sh-Polypeptide-93 allowed in the EU?

sh-Polypeptide-93 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does sh-Polypeptide-93 do in cosmetics?

sh-Polypeptide-93 functions as: Anti-aging, firming, smoothing, regeneration booster — recombinant human CTGF (Connective Tissue Growth Factor) analog, 324 amino acids. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for sh-Polypeptide-93?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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