Silybum Marianum Fruit Extract

INCI: SILYBUM MARIANUM FRUIT EXTRACT

CAS Number
84604-20-6
Function
Skin Conditioning, Antioxidant
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; silymarin (active) has GRAS status for supplements; no specific cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Asteraceae allergy cross-reactivity possible; active constituent is 80% silymarin / 30% silybin by HPLC . Ensure heavy metal and pesticide specs are within limits

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Concern Level: Low

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Silybum Marianum Fruit Extract safe in cosmetics?

Asteraceae allergy cross-reactivity possible; active constituent is 80% silymarin / 30% silybin by HPLC . Ensure heavy metal and pesticide specs are within limits The EU classifies Silybum Marianum Fruit Extract as "permitted". Safety rating: GOOD.

Is Silybum Marianum Fruit Extract allowed in the EU?

Silybum Marianum Fruit Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Silybum Marianum Fruit Extract do in cosmetics?

Silybum Marianum Fruit Extract functions as: Skin Conditioning, Antioxidant. It is classified as a cosmetic ingredient in our database. CAS number: 84604-20-6.

What is the Margin of Safety for Silybum Marianum Fruit Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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