Sodium Hexyldiphenyl Ether Sulfonate
INCI: SODIUM HEXYLDIPHENYL ETHER SULFONATE
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
10 study endpoints found for Sodium Hexyldiphenyl Ether Sulfonate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 128 mg/kg bw/day | oral | dog | oral | REACH |
| NOEL | 150 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 131 mg/kg bw/day | oral | dog | oral | REACH |
| NOEL | 0.3 other | oral | rat | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | dog | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 25 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 271 other | oral | rat | oral | REACH |
| NOAEL | 100 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 200 mg/kg bw/day | oral | dog | oral | REACH |
Expert Verdict
Primarily used as a hydrotrope/coupling agent in cleanser formulations. Diphenyl ether backbone raises environmental persistence questions. Predominantly rinse-off use recommended
Frequently Asked Questions
Is Sodium Hexyldiphenyl Ether Sulfonate safe in cosmetics?
Primarily used as a hydrotrope/coupling agent in cleanser formulations. Diphenyl ether backbone raises environmental persistence questions. Predominantly rinse-off use recommended The EU classifies Sodium Hexyldiphenyl Ether Sulfonate as "permitted". Safety rating: GOOD. 10 toxicological study endpoint(s) are available in our database.
Is Sodium Hexyldiphenyl Ether Sulfonate allowed in the EU?
Sodium Hexyldiphenyl Ether Sulfonate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Hexyldiphenyl Ether Sulfonate do in cosmetics?
Sodium Hexyldiphenyl Ether Sulfonate functions as: Surfactant (hydrotrope, coupling agent, solubilizer). It is classified as a cosmetic ingredient in our database. CAS number: 147732-60-3.
What is the Margin of Safety for Sodium Hexyldiphenyl Ether Sulfonate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Hexyldiphenyl Ether Sulfonate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Hexyldiphenyl Ether Sulfonate is 128 mg/kg bw/day based on a oral study via oral route in dog. A total of 10 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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