Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Sodium Laureth-12 Sulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
| LOAEL | 150 other | dermal | code:3484 | dermal | REACH |
| NOAEL | 50 mg/kg bw/day | oral | rat | oral | REACH |
| LOEL | 508 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Dermal and ocular irritant . 1,4-dioxane contamination risk from ethoxylation — critical to test (12 EO = higher risk) . More irritating than carboxylate counterparts. Concentration-dependent irritation.
Regulatory Flags
Frequently Asked Questions
Is Sodium Laureth-12 Sulfate safe in cosmetics?
Dermal and ocular irritant . 1,4-dioxane contamination risk from ethoxylation — critical to test (12 EO = higher risk) . More irritating than carboxylate counterparts. Concentration-dependent irritation. The EU classifies Sodium Laureth-12 Sulfate as "permitted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is Sodium Laureth-12 Sulfate allowed in the EU?
Sodium Laureth-12 Sulfate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Laureth-12 Sulfate do in cosmetics?
Sodium Laureth-12 Sulfate functions as: Cleansing, foaming, emulsifying surfactant. It is classified as a cosmetic ingredient in our database. CAS number: 9004-82-4.
What is the Margin of Safety for Sodium Laureth-12 Sulfate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Laureth-12 Sulfate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Laureth-12 Sulfate is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
Check Sodium Laureth-12 Sulfate compliance across multiple jurisdictions:
Related Ingredients
Is Sodium Laureth-12 Sulfate in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Sodium Laureth-12 Sulfate in your formulation.