Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
5 study endpoints found for Sodium Persulfate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 3000 ppm | oral | rat | oral | REACH |
| NOAEL | 131.5 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 41.1 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 131.5 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | 41.1 mg/kg bw/day | oral | - | oral | REACH |
GHS Hazard Classification
Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.
Expert Verdict
Strong sensitizer; anaphylactic reactions reported; occupational hazard for salon workers; CIR explicitly states data insufficient for leave-on use; EU requires label warnings
Regulatory Flags
Frequently Asked Questions
Is Sodium Persulfate safe in cosmetics?
Strong sensitizer; anaphylactic reactions reported; occupational hazard for salon workers; CIR explicitly states data insufficient for leave-on use; EU requires label warnings The EU classifies Sodium Persulfate as "restricted". Safety rating: MODERATE. 5 toxicological study endpoint(s) are available in our database.
Is Sodium Persulfate allowed in the EU?
Sodium Persulfate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Persulfate do in cosmetics?
Sodium Persulfate functions as: Oxidizing agent (hair colorants \& lighteners). It is classified as a cosmetic ingredient in our database. CAS number: 7775-27-1.
What is the Margin of Safety for Sodium Persulfate?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Persulfate?
The NOAEL (No Observed Adverse Effect Level) for Sodium Persulfate is 3000 ppm based on a oral study via oral route in rat. A total of 5 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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