4-Nitrophenyl Aminoethylurea
INCI: 4-NITROPHENYL AMINOETHYLUREA
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for 4-Nitrophenyl Aminoethylurea. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| LOAEL | 1 mg/kg bw/day | oral | rat | Subchronic | COSMOS_DB |
Expert Verdict
Nitro-aromatic amine structural class raises mutagenicity alerts; must comply with Annex III hair dye conditions including mandatory patch test warnings on labeling
Regulatory Flags
Frequently Asked Questions
Is 4-Nitrophenyl Aminoethylurea safe in cosmetics?
Nitro-aromatic amine structural class raises mutagenicity alerts; must comply with Annex III hair dye conditions including mandatory patch test warnings on labeling The EU classifies 4-Nitrophenyl Aminoethylurea as "restricted". Safety rating: MODERATE. 1 toxicological study endpoint(s) are available in our database.
Is 4-Nitrophenyl Aminoethylurea allowed in the EU?
4-Nitrophenyl Aminoethylurea EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does 4-Nitrophenyl Aminoethylurea do in cosmetics?
4-Nitrophenyl Aminoethylurea functions as: Hair dye (direct / semi-permanent, yellow shade). It is classified as a cosmetic ingredient in our database. CAS number: 27080-42-8.
What is the Margin of Safety for 4-Nitrophenyl Aminoethylurea?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 4-Nitrophenyl Aminoethylurea?
The NOAEL (No Observed Adverse Effect Level) for 4-Nitrophenyl Aminoethylurea is 1 mg/kg bw/day based on a Subchronic study via oral route in rat. Source: COSMOS_DB.
Compliance Tools
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Related Ingredients
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