Sodium Propylparaben
INCI: SODIUM PROPYLPARABEN
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for Sodium Propylparaben. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >=1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 980.9 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | 980.9 mg/kg bw/day | oral | - | oral | REACH |
| NOAEL | >1000 mg/kg bw/day | oral | - | oral | REACH |
Sensitization Profile
Contact sensitization data for Sodium Propylparaben based on clinical patch test studies and IFRA standards.
Source: ESSCA; IVDK; SCCS/1348/10
Expert Verdict
Endocrine disruption debate — SCCS concluded not a proven endocrine disruptor, not genotoxic, not carcinogenic ; critical: convert salt-to-acid for compliance — molecular weight correction required for PIF documentation ; prohibited in products for children under 3 years for the nappy area
Regulatory Flags
Frequently Asked Questions
Is Sodium Propylparaben safe in cosmetics?
Endocrine disruption debate — SCCS concluded not a proven endocrine disruptor, not genotoxic, not carcinogenic ; critical: convert salt-to-acid for compliance — molecular weight correction required for PIF documentation ; prohibited in products for children under 3 years for the nappy area The EU classifies Sodium Propylparaben as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.
Is Sodium Propylparaben allowed in the EU?
Sodium Propylparaben EU regulatory status: permitted. Maximum allowed concentration: 0.14%. This is based on EU Regulation 1223/2009 and its amendments.
What does Sodium Propylparaben do in cosmetics?
Sodium Propylparaben functions as: Preservative (antimicrobial); water-soluble sodium salt form of propylparaben. It is classified as a cosmetic ingredient in our database. CAS number: 35285-69-9.
What is the Margin of Safety for Sodium Propylparaben?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Sodium Propylparaben?
The NOAEL (No Observed Adverse Effect Level) for Sodium Propylparaben is >=1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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