Sorbitol Polyglycidyl Ether

INCI: SORBITOL POLYGLYCIDYL ETHER

CAS Number
68411-72-3 (typical; varies by degree of polymerization)
Function
Crosslinking agent; not a typical cosmetic emulsifier — primarily industrial use
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not listed in VCRP for cosmetic use; no CIR review

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major concern: Glycidyl ether functionality is reactive/electrophilic. Epoxide groups are associated with mutagenicity, skin sensitization, and irritation. NOT a standard cosmetic ingredient. Requires thorough safety dossier if intended for cosmetic use. Do NOT assume interchangeability with sorbitan esters

⚠️
Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Sorbitol Polyglycidyl Ether safe in cosmetics?

Major concern: Glycidyl ether functionality is reactive/electrophilic. Epoxide groups are associated with mutagenicity, skin sensitization, and irritation. NOT a standard cosmetic ingredient. Requires thorough safety dossier if intended for cosmetic use. Do NOT assume interchangeability with sorbitan esters The EU classifies Sorbitol Polyglycidyl Ether as "permitted". Safety rating: MODERATE.

Is Sorbitol Polyglycidyl Ether allowed in the EU?

Sorbitol Polyglycidyl Ether EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Sorbitol Polyglycidyl Ether do in cosmetics?

Sorbitol Polyglycidyl Ether functions as: Crosslinking agent; not a typical cosmetic emulsifier — primarily industrial use. It is classified as a cosmetic ingredient in our database. CAS number: 68411-72-3 (typical; varies by degree of polymerization).

What is the Margin of Safety for Sorbitol Polyglycidyl Ether?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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