Is Sphingolipids safe in cosmetics?
Sphingolipids has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Sphingolipids
INCI: SPHINGOLIPIDS
Sphingolipids (CAS 85116-74-1) is a cosmetic cosmetic ingredient functioning as Skin conditioning, emollient, skin protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 85116-74-1 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, emollient, skin protecting
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
2-hydroxy-N-[(E,2S,3R)-3-hydroxy-1-[(2R,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyoctadec-4-en-2-yl]tetracosanamide
InChIKey
ZXWQZGROTQMXME-WXUJBLQXSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; falls within the ceramide family reviewed by CIR as "safe as used"
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Sphingolipids.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
4 property records from structured ingredient metadata.
cost_pricing
{"cost_tier": "premium", "estimated_cost_per_kg_usd_low": "280", "estimated_cost_per_kg_usd_high": "520", "natural_premium_markup_pct": "0", "organic_certified_premium_pct": "0", "supply_chain_volatility": "medium", "primary_source_region": "Japan/Europe", "bulk_discount_threshold_kg": "5", "seasonal_price_variation": "low", "commodity_or_specialty": "specialty", "substitute_ingredients": "Ceramid…
hair_care
{"hair_function": "strengthening", "hair_type_suitability": "all", "curl_pattern_suitability": "all", "porosity_suitability": "high", "protein_sensitivity": "balanced", "moisture_protein_balance": "yes", "cg_method_approved": "not-a-silicone", "silicone_type": "not-a-sulfate", "sulfate_type": "no", "drying_alcohol": "no", "fatty_alcohol": "no", "heat_protectant": "yes", "color_safe": "strengthens"…
pregnancy_detail
{"pregnancy_safe": "yes", "breastfeeding_safe": "yes", "risk_category": "not-rated", "reason": "Safe; barrier lipids", "source": "dermatology literature"}
supply_chain
{"primary_producing_countries": "Germany, Japan, USA", "secondary_producing_countries": "France, Switzerland, South Korea", "raw_material_origin": "synthetic", "agricultural_crop_or_wild_harvested": "fermentation_extraction", "cultivation_climate_required": "biotech", "harvest_season": "continuous", "annual_global_production_tonnes": "180", "market_share_top_producer_pct": "68", "supply_chain_leng…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Sphingolipids.
Chemical Function
Softener and conditioner
Humectant
Regulatory Lists
Canada; Personal care; Substances in PCP - Canada (4/2014)
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Sphingolipids allowed in the EU?
Sphingolipids EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Sphingolipids do in cosmetics?
Sphingolipids functions as: Skin conditioning, emollient, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 85116-74-1.
Compliance Tools
Check Sphingolipids compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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