Is Strontium Hydroxide safe in cosmetics?
Strontium Hydroxide has a safety rating of "MODERATE" in our database. EU status: restricted. US status: permitted. 1 toxicological study endpoint(s) are available in our database.
Strontium Hydroxide
Also known as: Strontium hydroxide (Sr(OH)2), Strontium dihydroxide, EINECS No.: 242-367-1
INCI: STRONTIUM HYDROXIDE
Strontium Hydroxide (CAS 18480-07-4) is a cosmetic cosmetic ingredient functioning as pH adjuster for depilatories. Reported NOAEL =1000 mg/kg bw/day in Rat (ToxValDB_ECHA_IUCLID); EU Regulation 1223/2009 status: restricted, max 3.5%. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 18480-07-4 →
Auto-generated CPSR Part A draft with source citations
Cross-Vertical Regulatory Divergence
Strontium Hydroxide is classified GHS Danger (H302, H314, H318) in the chemicals database but is restricted in EU cosmetics at max 3.5%.
Source: Cosmetics: ingredients.eu_status/eu_max; Chemicals: ghs_classifications.signal_word/hazard_statement_code
Function
pH adjuster for depilatories
Safety Rating
MODERATE
Chemistry & Identifiers
IUPAC Name
strontium dihydroxide
InChIKey
UUCCCPNEFXQJEL-UHFFFAOYSA-L
Regulatory Status
EU EU Status
restricted
EU Max Conc.
3.5%
US US Status
permitted
US Notes
Permitted as cosmetic ingredient; no specific FDA restriction
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Strontium Hydroxide.
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for Strontium Hydroxide. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | =1000 mg/kg bw/day | oral | Rat | reproduction developmental | ToxValDB_ECHA_IUCLID |
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
100 - 1,000 tonnes
Substance Type
SUBSTANCE; GROUP
SVHC Candidate
No
Expanded Jurisdictional Detail
Additional regulatory detail beyond the 7-jurisdiction summary: Saudi SFDA, Korea MFDS, ASEAN ACD, Japan/Korea, Brazil/India, and cross-jurisdictional restriction entries.
SA Saudi SFDA (III - Restricted)
Product type: pH-adjuster for depilatories. Max: 3.5% (as strontium).
BRIN Brazil/India Cosmetics
India: Restricted · max 3.5% (as strontium)
Additional Jurisdictional Restrictions (2)
| Jurisdiction | Status | Max % | Product Type |
|---|---|---|---|
| IN | restricted | 3.5 | depilatory products (hair removing) |
| ASEAN | restricted | 3.5% as strontium; pH ≤12.7 | Depilatories |
Function Categories & List Membership
Regulatory List Membership (1)
EU CosIng Cosmetics Ingredient Database
Expert Verdict
Expert safety assessment and concern-level summary for Strontium Hydroxide.
Regulatory Flags
eu_cosing_listed
NOAEL Studies Summary
View details ->Public NOAEL study rows linked to Strontium Hydroxide by CAS number or substance name.
Studies
37
Lowest NOAEL
7.4 mg/kg bw/day
Highest NOAEL
1500 mg/kg bw/day
ToxValDB_ECHA_IUCLID
ECHA_REACH_reach_study_results_dossiers_23-05-2023.zip
Known Synonyms
Strontium hydroxide (Sr(OH)2)
Strontium dihydroxide
EINECS No.: 242-367-1
Regulatory Lists
Europe; Personal care; restricted
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Strontium Hydroxide allowed in the EU?
Strontium Hydroxide EU regulatory status: restricted. Maximum allowed concentration: 3.5%. This is based on EU Regulation 1223/2009 and its amendments.
What does Strontium Hydroxide do in cosmetics?
Strontium Hydroxide functions as: pH adjuster for depilatories. It is classified as a cosmetic ingredient in our database. CAS number: 18480-07-4.
What is the NOAEL for Strontium Hydroxide?
The NOAEL (No Observed Adverse Effect Level) for Strontium Hydroxide is =1000 mg/kg bw/day based on a reproduction developmental study via oral route in Rat. Source: ToxValDB_ECHA_IUCLID.
Is Strontium Hydroxide used outside cosmetics?
Strontium Hydroxide also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Strontium Hydroxide have different safety status in cosmetics vs industrial chemicals?
Strontium Hydroxide is classified GHS Danger (H302, H314, H318) in the chemicals database but is restricted in EU cosmetics at max 3.5%.
Compliance Tools
Check Strontium Hydroxide compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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