Good Cosmetic Ingredient NOAEL Data

TAED

CAS Number
10543-57-4
Function
Bleaching
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

4 study endpoints found for TAED. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 90 mg/kg bw/day oral rat oral REACH
NOEL 200 mg/kg bw/day dermal rat dermal REACH
NOAEL 200 mg/kg bw/day oral rat oral REACH
NOEL >=25 mg/kg bw/day oral rat oral REACH

Expert Verdict

TAED is listed in the EU CosIng database with functions: Bleaching It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment epa_safer_alternative

Frequently Asked Questions

Is TAED safe in cosmetics?

TAED is listed in the EU CosIng database with functions: Bleaching It is permitted in the EU without specific restrictions. The EU classifies TAED as "Permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is TAED allowed in the EU?

TAED EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does TAED do in cosmetics?

TAED functions as: Bleaching. It is classified as a cosmetic ingredient in our database. CAS number: 10543-57-4.

What is the NOAEL for TAED?

The NOAEL (No Observed Adverse Effect Level) for TAED is 90 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

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