Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
4 study endpoints found for TAED (Tetraacetylethylenediamine). NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | 90 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | 200 mg/kg bw/day | dermal | rat | dermal | REACH |
| NOAEL | 200 mg/kg bw/day | oral | rat | oral | REACH |
| NOEL | >=25 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
Primary use is industrial (laundry detergents). Strong oxidizing chemistry – requires careful concentration control in cosmetic applications. Eye/mucous membrane irritant. Ensure cosmetic-grade purity
Regulatory Flags
Frequently Asked Questions
Is TAED (Tetraacetylethylenediamine) safe in cosmetics?
Primary use is industrial (laundry detergents). Strong oxidizing chemistry – requires careful concentration control in cosmetic applications. Eye/mucous membrane irritant. Ensure cosmetic-grade purity The EU classifies TAED (Tetraacetylethylenediamine) as "permitted". Safety rating: MODERATE. 4 toxicological study endpoint(s) are available in our database.
Is TAED (Tetraacetylethylenediamine) allowed in the EU?
TAED (Tetraacetylethylenediamine) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does TAED (Tetraacetylethylenediamine) do in cosmetics?
TAED (Tetraacetylethylenediamine) functions as: Bleaching agent (hair/skin lightening); oxygen bleach activator. It is classified as a cosmetic ingredient in our database. CAS number: 10543-57-4.
What is the Margin of Safety for TAED (Tetraacetylethylenediamine)?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for TAED (Tetraacetylethylenediamine)?
The NOAEL (No Observed Adverse Effect Level) for TAED (Tetraacetylethylenediamine) is 90 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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