Good Cosmetic Ingredient NOAEL Data

Tamarindus Indica Extract

INCI: TAMARINDUS INDICA EXTRACT

CAS Number
84961-62-6
Function
Skin conditioning; contains alpha-hydroxy acids (notably tartaric acid) with kerato-regulatory properties
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Tamarindus Indica Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB

Expert Verdict

AHA activity means sun sensitivity warning may be needed; ensure extract is tested for pesticide residues and heavy metals per botanical raw material standards

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Concern Level: Low

Regulatory Flags

plant-extract natural-origin fda_food_additive

Frequently Asked Questions

Is Tamarindus Indica Extract safe in cosmetics?

AHA activity means sun sensitivity warning may be needed; ensure extract is tested for pesticide residues and heavy metals per botanical raw material standards The EU classifies Tamarindus Indica Extract as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is Tamarindus Indica Extract allowed in the EU?

Tamarindus Indica Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tamarindus Indica Extract do in cosmetics?

Tamarindus Indica Extract functions as: Skin conditioning; contains alpha-hydroxy acids (notably tartaric acid) with kerato-regulatory properties. It is classified as a cosmetic ingredient in our database. CAS number: 84961-62-6.

What is the Margin of Safety for Tamarindus Indica Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Tamarindus Indica Extract?

The NOAEL (No Observed Adverse Effect Level) for Tamarindus Indica Extract is 1000 mg/kg bw/day based on a Short Term Toxicity study via oral route in mouse. A total of 3 study endpoints are available. Source: COSMOS_DB.

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