Good Cosmetic Ingredient NOAEL Data

Tamarindus Indica Fruit/Seed Extract

INCI: TAMARINDUS INDICA FRUIT/SEED EXTRACT

CAS Number
84961-62-6
Function
Skin conditioning, moisturizing; polysaccharide and polyphenol content
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; no specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

3 study endpoints found for Tamarindus Indica Fruit/Seed Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 1000 mg/kg bw/day oral mouse Short Term Toxicity COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB
NOAEL 15000 mg/kg bw/day oral mouse Special Toxicology Study COSMOS_DB

Expert Verdict

Ensure supplier specification distinguishes fruit vs. seed fractions for batch consistency; test for pesticide residues and microbial contamination

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Concern Level: Low

Regulatory Flags

plant-extract fda_food_additive

Frequently Asked Questions

Is Tamarindus Indica Fruit/Seed Extract safe in cosmetics?

Ensure supplier specification distinguishes fruit vs. seed fractions for batch consistency; test for pesticide residues and microbial contamination The EU classifies Tamarindus Indica Fruit/Seed Extract as "permitted". Safety rating: GOOD. 3 toxicological study endpoint(s) are available in our database.

Is Tamarindus Indica Fruit/Seed Extract allowed in the EU?

Tamarindus Indica Fruit/Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tamarindus Indica Fruit/Seed Extract do in cosmetics?

Tamarindus Indica Fruit/Seed Extract functions as: Skin conditioning, moisturizing; polysaccharide and polyphenol content. It is classified as a cosmetic ingredient in our database. CAS number: 84961-62-6.

What is the Margin of Safety for Tamarindus Indica Fruit/Seed Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Tamarindus Indica Fruit/Seed Extract?

The NOAEL (No Observed Adverse Effect Level) for Tamarindus Indica Fruit/Seed Extract is 1000 mg/kg bw/day based on a Short Term Toxicity study via oral route in mouse. A total of 3 study endpoints are available. Source: COSMOS_DB.

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