Moderate Cosmetic Ingredient

TDI/Trimellitic Anhydride Copolymer

INCI: TDI/TRIMELLITIC ANHYDRIDE COPOLYMER

CAS Number
Not assigned in CosIng
Function
Film Former (primarily in nail products)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes CIR assessed trimellitic anhydride copolymers — data insufficient for safety determination outside nail products

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR concluded safe ONLY in nail product formulations at current use concentrations; insufficient data for all other cosmetic applications; must verify absence of residual free TDI and free trimellitic anhydride monomers; trimellitic anhydride causes respiratory irritation at low concentrations (NOAEL 3.3 mg/m³ in rats)

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Concern Level: Moderate

Frequently Asked Questions

Is TDI/Trimellitic Anhydride Copolymer safe in cosmetics?

CIR concluded safe ONLY in nail product formulations at current use concentrations; insufficient data for all other cosmetic applications; must verify absence of residual free TDI and free trimellitic anhydride monomers; trimellitic anhydride causes respiratory irritation at low concentrations (NOAEL 3.3 mg/m³ in rats) The EU classifies TDI/Trimellitic Anhydride Copolymer as "permitted". Safety rating: MODERATE.

Is TDI/Trimellitic Anhydride Copolymer allowed in the EU?

TDI/Trimellitic Anhydride Copolymer EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does TDI/Trimellitic Anhydride Copolymer do in cosmetics?

TDI/Trimellitic Anhydride Copolymer functions as: Film Former (primarily in nail products). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng.

What is the Margin of Safety for TDI/Trimellitic Anhydride Copolymer?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check TDI/Trimellitic Anhydride Copolymer compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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