Is Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) safe in cosmetics?
Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®)
Also known as: 1-Propanone, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthalenyl)-, 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphtyl)propan-1-one, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-one, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphtyl)propane-1-one, 1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-on (+3 more)
INCI: TETRAHYDRO-DIMETHYLNAPHTHYL-PROPAN-1-ONE
Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) (CAS 74499-60-8) is a cosmetic cosmetic ingredient functioning as Fragrance – macrocyclic musk-type ketone. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 74499-60-8 →
Auto-generated CPSR Part A draft with source citations
Function
Fragrance – macrocyclic musk-type ketone
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
1-(4,4-dimethyl-2,3-dihydro-1H-naphthalen-1-yl)propan-1-one
InChIKey
GNONYQJSCSRZOC-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not restricted; TSCA listed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®).
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Fragrance
Regulatory List Membership (1)
IFRA Fragrance Transparency List
Expert Verdict
Expert safety assessment and concern-level summary for Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®).
Regulatory Flags
fragrance-component
ifra_fragrance
Known Synonyms
1-Propanone, 1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthalenyl)-
1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphtyl)propan-1-one
1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-one
1-(1,2,3,4-tetrahydro-4,4-dimethyl-1-naphtyl)propane-1-one
1-(1,2,3,4-Tetrahydro-4,4-dimethyl-1-naphthyl)propan-1-on
1-(4,4-Dimethyl-1,2,3,4-tetrahydronaphthyl)propan-1-one
1-Propionyl-4,4-dimethyl-1,2,3,4-tetrahydronaphthalene
1-(4,4-Dimethyl-1,2,3,4-tetrahydronaphthalen-1-yl)propan-1-one
Chemical Function
Fragrance
Regulatory Lists
IFRA Transparency
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) allowed in the EU?
Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) do in cosmetics?
Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) functions as: Fragrance – macrocyclic musk-type ketone. It is classified as a cosmetic ingredient in our database. CAS number: 74499-60-8.
Is Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) used outside cosmetics?
Tetrahydro-dimethylnaphthyl-propan-1-one (Muscenone®) also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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