Is Tetrahydrofurfuryl Acetate safe in cosmetics?
Tetrahydrofurfuryl Acetate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Tetrahydrofurfuryl Acetate
INCI: TETRAHYDROFURFURYL ACETATE
Tetrahydrofurfuryl Acetate (CAS 637-64-9) is a cosmetic cosmetic ingredient functioning as Fragrance, Solvent. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
Cross-Vertical Regulatory Divergence
Tetrahydrofurfuryl Acetate is classified GHS Danger (H360Df, H302) in the chemicals database but is allowed in EU cosmetics.
Source: Cosmetics: ingredients.eu status; Chemicals: ghs classifications.signal word/hazard statement code
Function
Fragrance, Solvent
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
oxolan-2-ylmethyl acetate
InChIKey
AAQDYYFAFXGBFZ-UHFFFAOYSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; also GRAS as flavor agent (FEMA)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrahydrofurfuryl Acetate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Regulatory (2)
JECFA Number
1442
Source: WHO/JECFA
JECFA Evaluation
TETRAHYDROFURFURYL ACETATE | 2004 | No safety concern at current levels of intake when used as a flavouring agent | TRS 928-JECFA 63/106 | FAS 54-JECFA 63/487
Source: WHO/JECFA
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Deodorizer
Flavouring and nutrient
Solvent
Regulatory List Membership (1)
FDA Substances Added to Food (EAFUS)
Editorial summary
Preliminary editorial summary for Tetrahydrofurfuryl Acetate — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
fragrance-component
fda_food_additive
jecfa_safe
Chemical Function
Solvent
Deodorizer
Flavouring and nutrient
Regulatory Lists
Europe
food_additive; Substances Added to Food (formerly EAFUS) (2/2019)
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL2287522
Frequently Asked Questions
Is Tetrahydrofurfuryl Acetate allowed in the EU?
Tetrahydrofurfuryl Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrahydrofurfuryl Acetate do in cosmetics?
Tetrahydrofurfuryl Acetate functions as: Fragrance, Solvent. It is classified as a cosmetic ingredient in our database. CAS number: 637-64-9.
Is Tetrahydrofurfuryl Acetate used outside cosmetics?
Tetrahydrofurfuryl Acetate also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Does Tetrahydrofurfuryl Acetate have different safety status in cosmetics vs industrial chemicals?
Tetrahydrofurfuryl Acetate is classified GHS Danger (H360Df, H302) in the chemicals database but is allowed in EU cosmetics.
Compliance Tools
Check Tetrahydrofurfuryl Acetate compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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