Is Tetrapeptide-26 safe in cosmetics?
Tetrapeptide-26 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Tetrapeptide-26
INCI: TETRAPEPTIDE-26
Tetrapeptide-26 (CAS 1234463-61-6) is a cosmetic cosmetic ingredient functioning as Skin Conditioning; circadian rhythm regulation (boosts CLOCK gene and BMAL1. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 1234463-61-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin Conditioning; circadian rhythm regulation (boosts CLOCK gene and BMAL1 expression); anti-aging/DNA repair activation
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S)-2-[[(2S)-2-[[(2S)-1-[(2S)-2-amino-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-4-methylpentanoyl]amino]pentanediamide
InChIKey
XUMLWJDGGVUUNI-XUXIUFHCSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Not specifically regulated; permitted under general cosmetic provisions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tetrapeptide-26.
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Expert safety assessment and concern-level summary for Tetrapeptide-26.
Frequently Asked Questions
Is Tetrapeptide-26 allowed in the EU?
Tetrapeptide-26 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tetrapeptide-26 do in cosmetics?
Tetrapeptide-26 functions as: Skin Conditioning; circadian rhythm regulation (boosts CLOCK gene and BMAL1 expression); anti-aging/DNA repair activation. It is classified as a cosmetic ingredient in our database. CAS number: 1234463-61-6.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Perfuming
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