Tetrapeptide-3

INCI: ACETYL TETRAPEPTIDE-3

CAS Number
827306-88-7 (Acetyl Tetrapeptide-3); 1012317-71-3 (Caprooyl Tetrapeptide-3)
Function
Anti-aging; stimulates cell proliferation; biomimetic peptide mimicking natural peptides for hair follicle support and collagen synthesis
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CIR monograph for the base peptide; falls under general FDA cosmetic ingredient provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Limited independent toxicological data; SCCS has noted insufficient data quality in some peptide dossiers

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Concern Level: Moderate

Frequently Asked Questions

Is Tetrapeptide-3 safe in cosmetics?

Limited independent toxicological data; SCCS has noted insufficient data quality in some peptide dossiers The EU classifies Tetrapeptide-3 as "permitted". Safety rating: GOOD.

Is Tetrapeptide-3 allowed in the EU?

Tetrapeptide-3 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tetrapeptide-3 do in cosmetics?

Tetrapeptide-3 functions as: Anti-aging; stimulates cell proliferation; biomimetic peptide mimicking natural peptides for hair follicle support and collagen synthesis. It is classified as a cosmetic ingredient in our database. CAS number: 827306-88-7 (Acetyl Tetrapeptide-3); 1012317-71-3 (Caprooyl Tetrapeptide-3).

What is the Margin of Safety for Tetrapeptide-3?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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