Thymol Trimethoxycinnamate

INCI: THYMOL TRIMETHOXYCINNAMATE

CAS Number
504394-57-4
Function
Skin Conditioning; Anti-melanogenic / Skin Brightening (marketed as "Melasolv")
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically regulated; permitted under general cosmetic provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Relatively novel ingredient; PPARγ partial agonist activity — potential for systemic effects at high exposure not fully characterized . No CIR/SCCS monograph

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Concern Level: Low

Frequently Asked Questions

Is Thymol Trimethoxycinnamate safe in cosmetics?

Relatively novel ingredient; PPARγ partial agonist activity — potential for systemic effects at high exposure not fully characterized . No CIR/SCCS monograph The EU classifies Thymol Trimethoxycinnamate as "permitted". Safety rating: GOOD.

Is Thymol Trimethoxycinnamate allowed in the EU?

Thymol Trimethoxycinnamate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Thymol Trimethoxycinnamate do in cosmetics?

Thymol Trimethoxycinnamate functions as: Skin Conditioning; Anti-melanogenic / Skin Brightening (marketed as "Melasolv"). It is classified as a cosmetic ingredient in our database. CAS number: 504394-57-4.

What is the Margin of Safety for Thymol Trimethoxycinnamate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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