Good Cosmetic Ingredient NOAEL Data GHS Classified

TIN

CAS Number
7440-31-5
Function
Surfactant - Cleansing
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Toxicological Studies

2 study endpoints found for TIN. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL >1000 mg/kg bw/day oral rat oral REACH
NOAEL >1000 mg/kg bw/day oral rat oral REACH

GHS Hazard Classification

Globally Harmonized System classification per ECHA C&L inventory and ILO/WHO International Chemical Safety Cards.

Short-term Exposure Effects
May cause mechanical irritation to the respiratory tract.
Long-term Exposure Effects
The substance may have effects on the lungs. This may result in a benign pneumoconiosis (stannosis).

Expert Verdict

TIN is listed in the EU CosIng database with functions: Surfactant - Cleansing It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted surfactant needs-enrichment

Frequently Asked Questions

Is TIN safe in cosmetics?

TIN is listed in the EU CosIng database with functions: Surfactant - Cleansing It is permitted in the EU without specific restrictions. The EU classifies TIN as "Permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is TIN allowed in the EU?

TIN EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does TIN do in cosmetics?

TIN functions as: Surfactant - Cleansing. It is classified as a cosmetic ingredient in our database. CAS number: 7440-31-5.

What is the NOAEL for TIN?

The NOAEL (No Observed Adverse Effect Level) for TIN is >1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.

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