Is Tocopheryl Linoleate safe in cosmetics?
Tocopheryl Linoleate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Tocopheryl Linoleate
Also known as: 9,12-Octadecadienoic acid (9Z,12Z)-, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel-, (+/-)-α-Tocopherol linoleate, 9,12-Octadecadienoic acid (Z,Z)-, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-, 9,12-Octadecadienoic acid, (Z,Z)-, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+/-)-, dl-α-Tocopheryl linoleate (+1 more)
INCI: TOCOPHERYL LINOLEATE
Tocopheryl Linoleate (CAS 36148-84-2) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Conditioning, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
View industrial chemical safety profile for CAS 36148-84-2 →
Auto-generated CPSR Part A draft with source citations
Function
Antioxidant, Skin Conditioning, Skin Protecting
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] (9Z,12Z)-octadeca-9,12-dienoate
InChIKey
OFUHPGMOWVHNPN-QWZFGMNQSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR concluded safe as used in cosmetics; no specific FDA restrictions
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tocopheryl Linoleate.
Calculate MoS for your specific formulation with the MoS Calculator.
Additional Ingredient Properties
5 property records from structured ingredient metadata.
acne
{"cas_number": "111-02-4", "anti_acne_mechanism": "anti_inflammatory", "comedogenicity_rating_0_to_5": "3", "acne_type_efficacy": "inflammatory", "sebum_reduction_pct_clinical": "0-10", "prescription_required_usa": "No", "otc_drug_monograph_category": "No", "max_otc_concentration_pct": "No limit", "japan_quasi_drug_anti_acne": "No", "korea_functional_cosmetic_acne": "No", "eu_cosmetic_restriction_…
anti_pollution
{"cas_number": "111-11-5", "ingredient_class": "antioxidant_pollution_shield", "primary_mechanism": "chain_breaking", "pollution_types_targeted": "PM2_5/UV_A", "IR_A_protection": "no", "visible_light_protection": "no", "digital_screen_protection_claim": "no", "PAH_neutralization": "no", "ozone_protection": "no", "mitochondrial_protection": "no", "Nrf2_activation": "no", "AhR_pathway_modulation": "…
stability
{"shelf_life_months": "24", "shelf_life_opened_months": "12", "storage_temp_min_c": "4", "storage_temp_max_c": "25", "light_sensitive": "moderate", "air_sensitive": "yes", "moisture_sensitive": "no", "oxidation_prone": "yes", "requires_nitrogen_blanket": "no", "stability_indicator": "moderate", "degradation_products": "tocopherol, linoleic acid", "recommended_packaging": "amber glass", "antioxidan…
uv_stability
{"uv_stable": "yes", "uv_degradation_rate": "slow", "photosensitizer": "no", "phototoxic": "no", "photoallergic": "no", "requires_uv_protection_packaging": "no", "color_change_uv": "no", "odor_change_uv": "no", "efficacy_loss_uv_pct": "10", "spf_contribution": "no", "uva_protection": "no", "uvb_protection": "no", "photostable_sunscreen": "no", "boost_spf_of_others": "no", "antioxidant_under_uv": "…
vitamin
{"cas_number": "111-02-4", "ingredient_class": "vitamin_E", "chemical_form": "ester", "derivative_type": "stabilized", "molecular_weight_Da": "692.06", "water_solubility": "insoluble", "oil_solubility": "soluble", "log_P": "16.50", "stability_to_light": "good", "stability_to_heat": "good", "stability_to_oxidation": "good", "stability_to_pH_acid": "excellent", "stability_to_pH_alkaline": "excellent…
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Humectant
Softener and conditioner
Expert Verdict
Expert safety assessment and concern-level summary for Tocopheryl Linoleate.
Known Synonyms
9,12-Octadecadienoic acid (9Z,12Z)-, (2R)-3,4-dihydro-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-2H-1-benzopyran-6-yl ester, rel-
(+/-)-α-Tocopherol linoleate
9,12-Octadecadienoic acid (Z,Z)-, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-
9,12-Octadecadienoic acid, (Z,Z)-, 3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl ester, [2R*(4R*,8R*)]-(+/-)-
dl-α-Tocopheryl linoleate
Vitamin E Linoleate
Chemical Function
Antioxidant
Humectant
Softener and conditioner
Regulatory Lists
inert_ingredient; non_food_use; Pesticides
Australian Status
AICIS status: listed
Frequently Asked Questions
Is Tocopheryl Linoleate allowed in the EU?
Tocopheryl Linoleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tocopheryl Linoleate do in cosmetics?
Tocopheryl Linoleate functions as: Antioxidant, Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 36148-84-2.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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