Is Tocopheryl Nicotinate safe in cosmetics?
Tocopheryl Nicotinate has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Tocopheryl Nicotinate
INCI: TOCOPHERYL NICOTINATE
Tocopheryl Nicotinate (CAS 16676-75-8) is a cosmetic cosmetic ingredient functioning as Antioxidant, Skin Conditioning, Skin Protecting. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety data.
View industrial chemical safety profile for CAS 16676-75-8 →
Function
Antioxidant, Skin Conditioning, Skin Protecting
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Chemistry & Identifiers
IUPAC Name
[(2R)-2,5,7,8-tetramethyl-2-[(4R,8R)-4,8,12-trimethyltridecyl]-3,4-dihydrochromen-6-yl] pyridine-3-carboxylate
InChIKey
MSCCTZZBYHQMQJ-AZAGJHQNSA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
No specific FDA restrictions; present in 3 cosmetic formulations in 1998 VCRP at ≤1%
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Tocopheryl Nicotinate.
Calculate MoS for your specific formulation with the MoS Calculator.
PubChem Annotations
Safety and regulatory annotations from PubChem (NCBI) aggregated sources.
Safety (1)
Endocrine Disruptors
Potential endocrine disrupting compound
Source: NORMAN Suspect List Exchange
Editorial summary
Preliminary editorial summary for Tocopheryl Nicotinate — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Tocopheryl Nicotinate allowed in the EU?
Tocopheryl Nicotinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Tocopheryl Nicotinate do in cosmetics?
Tocopheryl Nicotinate functions as: Antioxidant, Skin Conditioning, Skin Protecting. It is classified as a cosmetic ingredient in our database. CAS number: 16676-75-8.
Is Tocopheryl Nicotinate used outside cosmetics?
Tocopheryl Nicotinate also appears in industrial chemical safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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Perfuming
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