Regulatory Status
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Safety Data
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Expert Verdict
Known sensitizer with IFRA use-level restrictions. Clastogenic in vitro (V79 cells) but NOT clastogenic in vivo. UV absorption coefficients exceed benchmark of concern — not photoirritating per in vitro 3T3-NRU assay, but photoallergenicity not yet evaluated
Regulatory Flags
Frequently Asked Questions
Is trans-Cinnamonitrile safe in cosmetics?
Known sensitizer with IFRA use-level restrictions. Clastogenic in vitro (V79 cells) but NOT clastogenic in vivo. UV absorption coefficients exceed benchmark of concern — not photoirritating per in vitro 3T3-NRU assay, but photoallergenicity not yet evaluated The EU classifies trans-Cinnamonitrile as "permitted". Safety rating: MODERATE.
Is trans-Cinnamonitrile allowed in the EU?
trans-Cinnamonitrile EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does trans-Cinnamonitrile do in cosmetics?
trans-Cinnamonitrile functions as: Perfuming (fragrance); warm-spicy, oily, slightly floral odor. It is classified as a cosmetic ingredient in our database. CAS number: 1885-38-7.
What is the Margin of Safety for trans-Cinnamonitrile?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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Related Ingredients
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