5-Methyl-5-Phenyl-3-Hexanone

INCI: 5-METHYL-5-PHENYL-3-HEXANONE

CAS Number
4927-36-0
Function
Fragrance (perfuming)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA; IFRA-regulated with maximum use levels per product category

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Confirmed skin sensitizer with Cramer Class II classification; IFRA maximum concentration in leave-on body products is 0.20%; predicted to be reactive with skin proteins in silico.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component ifra_fragrance

Frequently Asked Questions

Is 5-Methyl-5-Phenyl-3-Hexanone safe in cosmetics?

Confirmed skin sensitizer with Cramer Class II classification; IFRA maximum concentration in leave-on body products is 0.20%; predicted to be reactive with skin proteins in silico. The EU classifies 5-Methyl-5-Phenyl-3-Hexanone as "permitted". Safety rating: GOOD.

Is 5-Methyl-5-Phenyl-3-Hexanone allowed in the EU?

5-Methyl-5-Phenyl-3-Hexanone EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 5-Methyl-5-Phenyl-3-Hexanone do in cosmetics?

5-Methyl-5-Phenyl-3-Hexanone functions as: Fragrance (perfuming). It is classified as a cosmetic ingredient in our database. CAS number: 4927-36-0.

What is the Margin of Safety for 5-Methyl-5-Phenyl-3-Hexanone?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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