Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
May cross-react with tissue transglutaminase antibodies in celiac patients; ensure microbial purity of fermentation-derived product
Frequently Asked Questions
Is Transglutaminase safe in cosmetics?
May cross-react with tissue transglutaminase antibodies in celiac patients; ensure microbial purity of fermentation-derived product The EU classifies Transglutaminase as "permitted". Safety rating: GOOD.
Is Transglutaminase allowed in the EU?
Transglutaminase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Transglutaminase do in cosmetics?
Transglutaminase functions as: Skin conditioning / Hair conditioning — catalyzes protein cross-linking (glutamine–lysine isopeptide bonds). It is classified as a cosmetic ingredient in our database. CAS number: 300711-04-6.
What is the Margin of Safety for Transglutaminase?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
Check Transglutaminase compliance across multiple jurisdictions:
Related Ingredients
Is Transglutaminase in Your Products?
Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.
Try Piro Free →Analyze Your Full Ingredient List
Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Transglutaminase in your formulation.