Good Cosmetic Ingredient NOAEL Data

Trigonella Foenum-Graecum Seed Extract

INCI: TRIGONELLA FOENUM-GRAECUM SEED EXTRACT

CAS Number
84625-40-1
Function
Skin Conditioning, Masking, Perfuming
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted; fenugreek seed is GRAS for food and permitted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

2 study endpoints found for Trigonella Foenum-Graecum Seed Extract. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 33 mg/kg bw/day oral rat Short Term Toxicity COSMOS_DB
NOAEL 220 mg/kg bw/day oral rat Special Toxicology Study COSMOS_DB

Expert Verdict

Strong odor requiring masking in formulations; potential allergic reactions in individuals with Fabaceae (legume/peanut) allergies; patch test recommended

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Concern Level: Low

Regulatory Flags

plant-extract fragrance-component fda_food_additive

Frequently Asked Questions

Is Trigonella Foenum-Graecum Seed Extract safe in cosmetics?

Strong odor requiring masking in formulations; potential allergic reactions in individuals with Fabaceae (legume/peanut) allergies; patch test recommended The EU classifies Trigonella Foenum-Graecum Seed Extract as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.

Is Trigonella Foenum-Graecum Seed Extract allowed in the EU?

Trigonella Foenum-Graecum Seed Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trigonella Foenum-Graecum Seed Extract do in cosmetics?

Trigonella Foenum-Graecum Seed Extract functions as: Skin Conditioning, Masking, Perfuming. It is classified as a cosmetic ingredient in our database. CAS number: 84625-40-1.

What is the Margin of Safety for Trigonella Foenum-Graecum Seed Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Trigonella Foenum-Graecum Seed Extract?

The NOAEL (No Observed Adverse Effect Level) for Trigonella Foenum-Graecum Seed Extract is 33 mg/kg bw/day based on a Short Term Toxicity study via oral route in rat. A total of 2 study endpoints are available. Source: COSMOS_DB.

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