Triisotridecyl Trimellitate

INCI: TRIISOTRIDECYL TRIMELLITATE

CAS Number
72361-35-4
Function
Skin conditioning agent
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes CIR concluded safe in present practices of use when formulated to be non-irritating (IJT 43(Suppl. 1):96S-120S, 2024)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Must be formulated to be non-irritating; some trialkyl trimellitates showed slight dermal irritation at high concentrations in animal studies; in vitro estrogenic activity noted for analog (triethylhexyl trimellitate) but not relevant at dermal use due to negligible absorption

โš ๏ธ
Concern Level: Moderate

Frequently Asked Questions

Is Triisotridecyl Trimellitate safe in cosmetics?

Must be formulated to be non-irritating; some trialkyl trimellitates showed slight dermal irritation at high concentrations in animal studies; in vitro estrogenic activity noted for analog (triethylhexyl trimellitate) but not relevant at dermal use due to negligible absorption The EU classifies Triisotridecyl Trimellitate as "permitted". Safety rating: GOOD.

Is Triisotridecyl Trimellitate allowed in the EU?

Triisotridecyl Trimellitate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Triisotridecyl Trimellitate do in cosmetics?

Triisotridecyl Trimellitate functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 72361-35-4.

What is the Margin of Safety for Triisotridecyl Trimellitate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Triisotridecyl Trimellitate in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Triisotridecyl Trimellitate in your formulation.