Trimethyl-3-cyclohexene-1-methanethiol

INCI: TRIMETHYL-3-CYCLOHEXENE-1-METHANETHIOL

CAS Number
71159-90-5 (α,α,4-trimethylcyclohex-3-ene-1-methanethiol) ; R-enantiomer: 83150-78-1
Function
Fragrance ingredient — known as "Grapefruit Mercaptan"
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted in cosmetics and as GRAS flavoring agent

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Thiol compounds have very low odor thresholds; used at trace levels which inherently provides wide safety margins; standard thiol handling precautions (oxidation, stability)

⚠️
Concern Level: Low

Regulatory Flags

fragrance-component

Frequently Asked Questions

Is Trimethyl-3-cyclohexene-1-methanethiol safe in cosmetics?

Thiol compounds have very low odor thresholds; used at trace levels which inherently provides wide safety margins; standard thiol handling precautions (oxidation, stability) The EU classifies Trimethyl-3-cyclohexene-1-methanethiol as "permitted". Safety rating: GOOD.

Is Trimethyl-3-cyclohexene-1-methanethiol allowed in the EU?

Trimethyl-3-cyclohexene-1-methanethiol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trimethyl-3-cyclohexene-1-methanethiol do in cosmetics?

Trimethyl-3-cyclohexene-1-methanethiol functions as: Fragrance ingredient — known as "Grapefruit Mercaptan". It is classified as a cosmetic ingredient in our database. CAS number: 71159-90-5 (α,α,4-trimethylcyclohex-3-ene-1-methanethiol) ; R-enantiomer: 83150-78-1.

What is the Margin of Safety for Trimethyl-3-cyclohexene-1-methanethiol?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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