Trimethylolpropane Tris-Mercaptopropionate

INCI: TRIMETHYLOLPROPANE TRIS-MERCAPTOPROPIONATE

CAS Number
33007-83-9
Function
Crosslinking agent, reducing agent (primarily industrial; limited direct cosmetic use)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically addressed for cosmetic use; no FDA prohibition

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

H315 skin irritation, H319 eye irritation, H335 respiratory irritation; harmful if swallowed (H302); strong thiol odor; primarily used as industrial crosslinker (thiol-ene chemistry); any cosmetic use requires full SCCS-level safety dossier

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Concern Level: Moderate

Frequently Asked Questions

Is Trimethylolpropane Tris-Mercaptopropionate safe in cosmetics?

H315 skin irritation, H319 eye irritation, H335 respiratory irritation; harmful if swallowed (H302); strong thiol odor; primarily used as industrial crosslinker (thiol-ene chemistry); any cosmetic use requires full SCCS-level safety dossier The EU classifies Trimethylolpropane Tris-Mercaptopropionate as "permitted". Safety rating: MODERATE.

Is Trimethylolpropane Tris-Mercaptopropionate allowed in the EU?

Trimethylolpropane Tris-Mercaptopropionate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Trimethylolpropane Tris-Mercaptopropionate do in cosmetics?

Trimethylolpropane Tris-Mercaptopropionate functions as: Crosslinking agent, reducing agent (primarily industrial; limited direct cosmetic use). It is classified as a cosmetic ingredient in our database. CAS number: 33007-83-9.

What is the Margin of Safety for Trimethylolpropane Tris-Mercaptopropionate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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