Tripotassium Glycyrrhizate

INCI: TRIPOTASSIUM GLYCYRRHIZATE

CAS Number
55824-09-2 (glycyrrhizic acid tripotassium salt)
Function
Skin conditioning agent (anti-inflammatory, soothing — licorice root derivative)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; related glycyrrhizate salts reviewed by CIR and found safe

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High oral doses of glycyrrhizin are associated with pseudoaldosteronism (hypertension, hypokalemia); not a concern at cosmetic dermal use levels. Ensure use concentration stays within established ranges

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Concern Level: Low

Frequently Asked Questions

Is Tripotassium Glycyrrhizate safe in cosmetics?

High oral doses of glycyrrhizin are associated with pseudoaldosteronism (hypertension, hypokalemia); not a concern at cosmetic dermal use levels. Ensure use concentration stays within established ranges The EU classifies Tripotassium Glycyrrhizate as "permitted". Safety rating: GOOD.

Is Tripotassium Glycyrrhizate allowed in the EU?

Tripotassium Glycyrrhizate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tripotassium Glycyrrhizate do in cosmetics?

Tripotassium Glycyrrhizate functions as: Skin conditioning agent (anti-inflammatory, soothing — licorice root derivative). It is classified as a cosmetic ingredient in our database. CAS number: 55824-09-2 (glycyrrhizic acid tripotassium salt).

What is the Margin of Safety for Tripotassium Glycyrrhizate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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