Poor Cosmetic Ingredient Sensitization Data

Tripropylene Glycol Diacrylate

INCI: TRIPROPYLENE GLYCOL DIACRYLATE

CAS Number
42978-66-5
Function
Nail product monomer (UV-curable resin component for artificial nails/gel polish)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted in cosmetics; no specific FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for Tripropylene Glycol Diacrylate based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
other
EU Allergen Listed
no
Patch Test Positive Rate
0.3%
Cross-reactivity Group
acrylate-group
Reaction Type
contact-dermatitis

Source: IVDK; ESSCA

Expert Verdict

Known contact allergen (acrylate monomer). Causes skin/eye/respiratory irritation. Occupational hazard for nail techs. Must ensure complete polymerization. Aquatic toxicity concern

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Concern Level: High

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Tripropylene Glycol Diacrylate safe in cosmetics?

Known contact allergen (acrylate monomer). Causes skin/eye/respiratory irritation. Occupational hazard for nail techs. Must ensure complete polymerization. Aquatic toxicity concern The EU classifies Tripropylene Glycol Diacrylate as "permitted". Safety rating: POOR.

Is Tripropylene Glycol Diacrylate allowed in the EU?

Tripropylene Glycol Diacrylate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Tripropylene Glycol Diacrylate do in cosmetics?

Tripropylene Glycol Diacrylate functions as: Nail product monomer (UV-curable resin component for artificial nails/gel polish). It is classified as a cosmetic ingredient in our database. CAS number: 42978-66-5.

What is the Margin of Safety for Tripropylene Glycol Diacrylate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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