Is Trilinolein safe in cosmetics?
Trilinolein has a safety rating of "EXCELLENT" in our database. EU status: permitted. US status: permitted.
Excellent
Cosmetic Ingredient
Trilinolein
Also known as: Trilinolein (trilinolein C18:2), EINECS 208-666-6, UNII-V5LJ52OGS7, 1,2,3-Propanetriol trilinoleate, 1,2,3-Propenetriol tri(9,12-octadecadienoate) (+15 more)
INCI: TRILINOLEIN
Trilinolein (CAS 537-40-6) is a cosmetic cosmetic ingredient functioning as Skin conditioning agent (occlusive), viscosity increasing agent (nonaqueous). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in pharmaceutical data.
View industrial chemical safety profile for CAS 537-40-6 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning agent (occlusive), viscosity increasing agent (nonaqueous)
Safety Rating
EXCELLENT
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted; reported in VCRP in night and other skin care preparations
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Trilinolein.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Humectant
Softener and conditioner
Solvent
Thickening agent
Viscosity modifier
Expert Verdict
Expert safety assessment and concern-level summary for Trilinolein.
Known Synonyms
Trilinolein (trilinolein C18:2)
EINECS 208-666-6
UNII-V5LJ52OGS7
1,2,3-Propanetriol trilinoleate
1,2,3-Propenetriol tri(9,12-octadecadienoate)
1,2,3-tri-(9Z,12Z)-octadecadienoylglycerol
1,2,3-tri-(9Z,12Z-octadecadienoyl)glycerol
1,3-bis[(9Z,12Z)-octadeca-9,12-dienoyloxy]propan-2-yl (9Z,12Z)-octadeca-9,12-dienoate
1-Linoleoyl-2-linoleoyl-3-linoleoyl-glycerol
TAG(18:2/18:2/18:2)
TAG(18:2n6/18:2n6/18:2n6)
TAG(18:2w6/18:2w6/18:2w6)
TAG(54:6)
TG [18:2(omega-6)/18:2(omega-6)/18:2(omega-6)]
TG(18:2(9Z,12Z)/18:2(9Z,12Z)/18:2(9Z,12Z))
TG(18:2/18:2/18:2)
TG(18:2n6/18:2n6/18:2n6)
TG(18:2omega6/18:2omega6/18:2omega6)
TG(18:2w6/18:2w6/18:2w6)
TG(54:6)
Chemical Function
Softener and conditioner
Viscosity modifier
Solvent
Humectant
Thickening agent
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL3343985
Frequently Asked Questions
Is Trilinolein allowed in the EU?
Trilinolein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Trilinolein do in cosmetics?
Trilinolein functions as: Skin conditioning agent (occlusive), viscosity increasing agent (nonaqueous). It is classified as a cosmetic ingredient in our database. CAS number: 537-40-6.
Is Trilinolein used outside cosmetics?
Trilinolein also appears in pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Trilinolein compliance across multiple jurisdictions:
Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
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