Xanthine

INCI: XANTHINE

CAS Number
69-89-6
Function
Skin conditioning
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted for cosmetic use; also a known biochemical (purine base) โ€” no specific FDA cosmetic restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Structurally related to caffeine/theophylline โ€” at very high systemic doses could have pharmacological (vasodilatory) effects, but not a concern at cosmetic topical levels

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Concern Level: Low

Frequently Asked Questions

Is Xanthine safe in cosmetics?

Structurally related to caffeine/theophylline โ€” at very high systemic doses could have pharmacological (vasodilatory) effects, but not a concern at cosmetic topical levels The EU classifies Xanthine as "permitted". Safety rating: GOOD.

Is Xanthine allowed in the EU?

Xanthine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Xanthine do in cosmetics?

Xanthine functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 69-89-6.

What is the Margin of Safety for Xanthine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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