Good Cosmetic Ingredient NOAEL Data

1,2-Dihydrolinalool

INCI: 1,2-DIHYDROLINALOOL

CAS Number
18479-58-8
Function
Fragrance
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restriction; FEMA GRAS; IFRA/RIFM assessed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

4 study endpoints found for 1,2-Dihydrolinalool. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOEL 50 mg/kg bw/day oral rat oral REACH
NOAEL 1000 mg/kg bw/day oral rat oral REACH
NOAEL 500 mg/kg bw/day oral - oral REACH
NOAEL 1000 mg/kg bw/day oral - oral REACH

Expert Verdict

Synthetic fragrance material with bois de rose, woody, and citrus odor profile; IFRA concentration limits apply.

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Concern Level: Low

Regulatory Flags

fragrance-component epa_safer_alternative ifra_fragrance

Frequently Asked Questions

Is 1,2-Dihydrolinalool safe in cosmetics?

Synthetic fragrance material with bois de rose, woody, and citrus odor profile; IFRA concentration limits apply. The EU classifies 1,2-Dihydrolinalool as "permitted". Safety rating: GOOD. 4 toxicological study endpoint(s) are available in our database.

Is 1,2-Dihydrolinalool allowed in the EU?

1,2-Dihydrolinalool EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 1,2-Dihydrolinalool do in cosmetics?

1,2-Dihydrolinalool functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 18479-58-8.

What is the Margin of Safety for 1,2-Dihydrolinalool?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for 1,2-Dihydrolinalool?

The NOAEL (No Observed Adverse Effect Level) for 1,2-Dihydrolinalool is 50 mg/kg bw/day based on a oral study via oral route in rat. A total of 4 study endpoints are available. Source: REACH.

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