Good Cosmetic Ingredient Sensitization Data

2,6-DIAMINOPYRIDINE

CAS Number
141-86-6
Function
Hair Dyeing
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status Permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status Not specifically regulated

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
NOAEL: 3 mg/kg bw/day | Source: SCCS/1503/13 (2013)
Dermal Absorption
0.98% (pig skin, OECD 428, 30 min exposure)

Calculate MoS for your specific formulation with the MoS Calculator.

Sensitization Profile

Contact sensitization data for 2,6-DIAMINOPYRIDINE based on clinical patch test studies and IFRA standards.

Sensitization Rate
low
Allergen Class
dye
EU Allergen Listed
no
Patch Test Positive Rate
0.2%
Cross-reactivity Group
para-amino-group
Reaction Type
contact-dermatitis

Source: SCCS; IVDK

Expert Verdict

2,6-DIAMINOPYRIDINE is listed in the EU CosIng database with functions: Hair Dyeing It is permitted in the EU without specific restrictions.

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Concern Level: Low

Regulatory Flags

cosing-sourced eu-permitted needs-enrichment eu_cosing_listed

Frequently Asked Questions

Is 2,6-DIAMINOPYRIDINE safe in cosmetics?

2,6-DIAMINOPYRIDINE is listed in the EU CosIng database with functions: Hair Dyeing It is permitted in the EU without specific restrictions. The EU classifies 2,6-DIAMINOPYRIDINE as "Permitted". Safety rating: GOOD.

Is 2,6-DIAMINOPYRIDINE allowed in the EU?

2,6-DIAMINOPYRIDINE EU regulatory status: Permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2,6-DIAMINOPYRIDINE do in cosmetics?

2,6-DIAMINOPYRIDINE functions as: Hair Dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 141-86-6.

What is the Margin of Safety for 2,6-DIAMINOPYRIDINE?

NOAEL: 3 mg/kg bw/day | Source: SCCS/1503/13 (2013) The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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