Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
1 study endpoint found for 2-Aminobutanol. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOEL | 10 mg/kg bw/day | oral | rat | oral | REACH |
Expert Verdict
As a secondary amine impurity source, the main risk is formation of nitrosamines (potentially carcinogenic) during manufacture or storage with nitrosating agents. This ingredient functions as a buffer in broader cosmetic categories. EU Annex III conditions are the critical compliance gate.
Frequently Asked Questions
Is 2-Aminobutanol safe in cosmetics?
As a secondary amine impurity source, the main risk is formation of nitrosamines (potentially carcinogenic) during manufacture or storage with nitrosating agents. This ingredient functions as a buffer in broader cosmetic categories. EU Annex III conditions are the critical compliance gate. The EU classifies 2-Aminobutanol as "restricted". Safety rating: GOOD. 1 toxicological study endpoint(s) are available in our database.
Is 2-Aminobutanol allowed in the EU?
2-Aminobutanol EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.
What does 2-Aminobutanol do in cosmetics?
2-Aminobutanol functions as: Buffering (pH adjuster). It is classified as a cosmetic ingredient in our database. CAS number: 96-20-8.
What is the Margin of Safety for 2-Aminobutanol?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for 2-Aminobutanol?
The NOAEL (No Observed Adverse Effect Level) for 2-Aminobutanol is 10 mg/kg bw/day based on a oral study via oral route in rat. Source: REACH.
Compliance Tools
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Related Ingredients
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