2-Cyanomethyl Benzimidazole

INCI: 2-CYANOMETHYL BENZIMIDAZOLE

CAS Number
4414-88-4
Function
Hair dyeing
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Listed in EPA TSCA inventory and FDA GSRS; no specific cosmetic ban

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Acute inhalation toxicity (GHS Category 4) with nitrile group present; limited cosmetic safety assessment data available and would require full SCCS dossier for EU Annex III listing if used in hair dyes; skin corrosion/irritation flagged in safety data.

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Concern Level: High

Frequently Asked Questions

Is 2-Cyanomethyl Benzimidazole safe in cosmetics?

Acute inhalation toxicity (GHS Category 4) with nitrile group present; limited cosmetic safety assessment data available and would require full SCCS dossier for EU Annex III listing if used in hair dyes; skin corrosion/irritation flagged in safety data. The EU classifies 2-Cyanomethyl Benzimidazole as "permitted". Safety rating: MODERATE.

Is 2-Cyanomethyl Benzimidazole allowed in the EU?

2-Cyanomethyl Benzimidazole EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Cyanomethyl Benzimidazole do in cosmetics?

2-Cyanomethyl Benzimidazole functions as: Hair dyeing. It is classified as a cosmetic ingredient in our database. CAS number: 4414-88-4.

What is the Margin of Safety for 2-Cyanomethyl Benzimidazole?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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