2-Dodecenal

INCI: 2-DODECENAL

CAS Number
4826-62-4
Function
Fragrance
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no FDA restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

α,β-unsaturated aldehyde with Michael acceptor reactivity and direct protein reactivity. Not genotoxic. Used as read-across analog for 2-tridecenal safety assessment.

⚠️
Concern Level: Moderate

Regulatory Flags

fragrance-component ifra_fragrance fda_food_additive jecfa_safe

Frequently Asked Questions

Is 2-Dodecenal safe in cosmetics?

α,β-unsaturated aldehyde with Michael acceptor reactivity and direct protein reactivity. Not genotoxic. Used as read-across analog for 2-tridecenal safety assessment. The EU classifies 2-Dodecenal as "permitted". Safety rating: MODERATE.

Is 2-Dodecenal allowed in the EU?

2-Dodecenal EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does 2-Dodecenal do in cosmetics?

2-Dodecenal functions as: Fragrance. It is classified as a cosmetic ingredient in our database. CAS number: 4826-62-4.

What is the Margin of Safety for 2-Dodecenal?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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